In laboratory rats, a low dose of aspirin usually suffices t

In laboratory rats, a low dose of aspirin usually suffices to block production of thromboxane, which is a substance that promotes blood clotting, but not seriously interfering with the production of prostacyclin, which prevents clotting.

(A) which is a substance that promotes blood clotting, but not seriously interfering
(B) a substance that promotes blood clotting, but not seriously interfering
(C) a substance that promotes blood clotting, but does not seriously interfere
(D) which is a substance to promote blood clotting, but does not seriously interfere
(E) which is a substance that promotes blood clotting, but not a serious interference